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"The MGED Ontology"

Ontology Container Information

Title:"The MGED Ontology" Classes:233
Creator:Chris Stoeckert, Helen Parkinson, Trish Whetzel, Paul Spellman, Catherine A. Ball, Joseph White, John Matese, Liju Fan, Gilberto Fragoso, Mervi Heiskanen, Susanna Sansone, Helen Causton, Laurence Game, Chris Taylor Properties:143
Subject:An ontology for microarray experiments in support of MAGE v.1. Individuals:681
Description:Concepts, definitions, terms, and resources for standardized description of a microarray experiment in support of MAGE v.1. The MGED ontology is divided into the MGED Core ontology which is intended to be stable and in synch with MAGE v.1; and the MGED Extended ontology which adds further associations and classes not found in MAGE v.1 Axioms:0
Date:Feb. 9, 2007
Version:"1.3.1.1"

Note that this page now reflects the latest version 1.3.1.1. The previous verion (1.2.0) displayed is still available as an OWL file (see link below)

Deprecated Biosequence terms

Several of the MO BioSequence Terms have been deprecated as they map directly to the Sequence Ontology terms. A mapping file for the MO to SO terms is available.

Notes and edits to MO 1.3

Notes files for changes in MO version 1.3.0 and MO version 1.3.1.

Notes and edits to MO 1.2

A notes file containing edits, bug fixes, and additions is provided to document changes.

Notes and edits to MO 1.1.7/8/9

A notes file containing edits, bug fixes, and additions is provided to document changes.

Ontology terms under review

A tracker on sourceforge has been set up for new terms.

Alternate views of the MGED Ontology

Gilberto Fragoso has adapted the MGED Ontology to be viewed using the NCI DTS Browser. This provides a class view and explicitly shows inerited properties.
A static view of the class hierarchy can be found here.

Files

OWL
http://mged.sourceforge.net/ontologies/MGEDOntology.owl#
OWL (previous version 1.3.0.1)
http://mged.sourceforge.net/ontologies/MGEDOntology.1.3.0.1.owl#
OWL (previous version 1.2.0)
http://mged.sourceforge.net/ontologies/MGEDOntology.1.2.0.owl#
OWL (previous version 1.1.9)
http://mged.sourceforge.net/ontologies/MGEDOntology.1.1.9.owl#
Please note that this file is not an exact match of MOv1.1.9 in DAML as a couple additional terms have been added.
DAML
http://mged.sourceforge.net/ontologies/MGEDOntology.daml#
DAML (previous version 1.1.9)
http://mged.sourceforge.net/ontologies/MGEDOntology.1.1.9.daml#
DAML (previous version 1.1.8)
http://mged.sourceforge.net/ontologies/MGEDOntology.1.1.8.daml#
RDFS
The RDFS file was found to be missing things and has been retired until a complete copy of the daml version is generated.

Classes



Action Age Allele ArrayDesignPackage ArrayGroup ArrayPackage Atmosphere AtomicAction AuditAndSecurityPackage BarrierFacility Bedding BibliographicReference BioAssay BioAssayData BioAssayDataCluster BioAssayDataPackage BioAssayPackage BioMaterial BioMaterialCharacteristicCategory BioMaterialCharacteristics BioMaterialPackage BioMaterialPurity BioMolecularAnnotation BioSample BioSampleType BioSequence BioSequencePackage BioSequenceType BioSource BioSourceProvider BioSourceType BiologicalFactorCategory BiologicalProperty Biometrics CancerSite CellLine CellLineDatabase CellType CellTypeDatabase CellularComponent CellularComponentDatabase ChromosomalAberration ChromosomalAberrationClassification ClinicalHistory ClinicalTreatment ClinicalTreatmentDatabase ComplexAction Compound CompoundDatabase ConcentrationUnit ConcentrationUnitOther Contact ControlType Cultivar DataTransformationProtocolType DataType Database DatabaseEntryType DefectType DeliveryMethod DeprecatedTerms DeprecationReason DerivedBioAssay DerivedBioAssayType DescriptionPackage DesignElement DesignElementGroup DesignElementGroupType DesignElementPackage DevelopmentalStage DevelopmentalStageDatabase DiseaseLocation DiseaseStaging DiseaseStagingDatabase DiseaseState DiseaseStateDatabase DistanceUnit DistanceUnitOther Ecotype EnvironmentalFactorCategory EnvironmentalHistory EnvironmentalStress EpidemiologicalDesign Experiment ExperimentDesign ExperimentDesignType ExperimentPackage ExperimentalFactor ExperimentalFactorCategory ExperimentalProtocolType FactorValue FactorValueDependency FactorValueSet FailType FamilyHistory FamilyMember FamilyRelationship FeatureDefect FeatureGroup FeatureShape Fiducial FiducialType Generation GeneticMaterial GeneticModification Genotype GeographicLocation GeographicLocationDatabase GrowthCondition Haplotype Hardware HardwareType HardwareVariation HigherLevelAnalysisPackage HigherLevelAnalysisProtocolType Histology HistologyDatabase HistoryFactor Host Humidity Image ImageFormat Individual IndividualChromosomalAbnormality IndividualGeneticCharacteristics InitialTimePoint LabelCompound LabeledExtract Light LightUnit MGEDCoreOntology MGEDExtendedOntology MGEDOntology MGEDOntologyVersion MassUnit MassUnitOther MaterialType Measurement MeasurementPackage MeasurementType Media MethodologicalDesign MethodologicalFactorCategory Node NodeValue NodeValueType NormalizationDescription NormalizationDescriptionType Nutrients Observation ObservationDatabase OntologyEntry OperatorVariation Organism OrganismDatabase OrganismPart OrganismPartDatabase OrganismStatus Organization OtherUnit Parameter PathogenTest Person PerturbationalDesign Phenotype PhenotypeDatabase PhysicalArrayDesign PhysicalBioAssay PhysicalBioSequenceType Ploidy PolymerType PopulationDensity Preservation PreservationType Protocol ProtocolPackage ProtocolParameterType ProtocolType ProtocolVariation PublicationType QualityControlDescription QualityControlDescriptionType QuantitationType QuantitationTypePackage QuantityUnit QuantityUnitOther RadiationUnit ReplicateDescription ReplicateDescriptionType Reporter Result Roles SamplingTimePoint Scale SeqFeatureBasis SequenceOntologyBioSequenceType SequenceOntologyDatabase Serotype Sex Software SoftwareType SoftwareVariation SomaticModification StrainOrLine StrainOrLineDatabase StrandType SubstrateType SurfaceType TargetedCellType TargetedCellTypeDatabase TechnologicalDesign TechnologyType Temperature TemperatureUnit Test TestResult TestType TestTypeDatabase TheoreticalBioSequenceType TimeUnit TimeUnitOther Transformation Treatment TumorGrading TumorGradingDatabase URI Unit User VolumeUnit VolumeUnitOther WarningType Water ZoneDefect

Properties

class_role class_source dc:contributor dc:coverage dc:creator dc:date dc:description dc:format dc:identifier dc:language dc:publisher dc:relation dc:rights dc:source dc:subject dc:title dc:type deprecated_from_version deprecation_in_version deprecation_old_parent deprecation_old_restriction deprecation_reason deprecation_replacement_term has_ID has_MAGE_description has_URI has_accession has_accession_version has_action has_additive has_address has_affiliation has_atmospheric_component has_authors has_been_treated has_bioassay_data has_bioassays has_biomaterial_characteristics has_biosource_type has_cancer_site has_category has_chromosomal_aberration_classification has_citation has_clinical_finding has_clinical_record has_clinical_treatment has_compound has_cubic_volume has_database has_database_entry_type has_description has_diameter has_disease_location has_disease_staging has_disease_state has_donor has_editor has_email has_experiment_design has_experiment_design_type has_experiment_factors has_factor_value has_factor_value_ontology_entry has_family_member has_family_relationship has_fax has_feature_shape has_fiducials has_first_name has_hardware has_height has_host has_host_part has_human_readable_URI has_image_format has_individual has_individual_genetic_characteristics has_initial_time_point has_issue has_laboratory_test has_last_name has_length has_machine_readable_URI has_make has_manufacturer has_mass has_maximum_measurement has_measurement has_measurement_type has_mid_initials has_model has_name has_node_value has_node_value_type has_nodes has_nutrient_component has_order has_organism_part has_owner has_pages has_parent_organization has_part_modified has_performer has_phone has_prior_disease_state has_property_set has_protocol has_providers has_publication has_publisher has_reason_for_deprecation has_result has_scale has_software has_species has_test_protocol has_test_result has_test_type has_text has_title has_toll_free_phone has_treatment has_type has_units has_value has_version has_volume has_year is_solvent is_user_defined protege:abstract protege:allowedParent protege:defaultLanguage protege:excludedTest protege:probeClass protege:readOnly protege:subclassesDisjoint protege:todoPrefix protege:todoProperty protege:usedLanguage replaced_with_term split_to_term synonym unique_identifier was_replaced_by was_tested_for xsp:base xsp:fractionDigits xsp:length xsp:maxExclusive xsp:maxInclusive xsp:maxLength xsp:minExclusive xsp:minInclusive xsp:minLength xsp:pattern xsp:totalDigits

Individuals

A ATCC_Cultures Adult_Mouse_Anatomy Affymetrix_DAT Affymetrix_average_difference BAC CABRI_Bacteria_and_Archaea_Strains CABRI_Filamentous_Fungi_Strains CABRI_HLA_typed_B_Cell_lines CABRI_Human_and_Animal_Cell_lines CABRI_Hybridomas CABRI_Yeasts_Strains CBIL_CV CLDB_Human_and_Animal_Cell_Line CellML ChEBI ChemID Ci Cy3 Cy5 DNA DNA_sequencer EMAP EST Euclidean_distance F FMA F_minus FlyBase_developmental_stage_database FlyBase_organism_part_database GIF GRAMENE GeneOntology HUMAT Hfr ICD-9-CM IU IUPAC_Clinical_Chemistry_Guidelines JAX_mouse_strains JPEG K L LOINC M MAD_stage MAS4_average_difference MAS5_signal MAS5_signal_log_ratio MBEI MESH MTB_Database Mammalian_Phenotype_Ontology NASC NCBI_taxonomy NCI_Thesaurus NCI_cell_type_database NCI_compound_database NCI_disease_staging_database NCI_disease_state_database NCI_geographic_location_database NCI_histology_database NCI_organism_part_database NCI_strain_or_line_database NCI_targeted_cell_type_database NCI_tumor_grading_database ORF PAC PCR PCR_amplicon PCR_amplification PCR_fail PCR_primer PCR_primer_forward PCR_primer_reverse PCR_questionable PNG Pathbase Pearson_correlation R RMA RNA RNA_stability_design Rad Rem SequenceOntology Spearmans_rank_correlation TAIR TAIR_arabidopsis_anatomy_ontology TAIR_arabidopsis_development_ontology TDMS TIFF UMLS U_per_L U_per_week WebRENI YAC _32P _33P absolute acclimatization acrossBioAssay_mean_and_coefficient_of_variation acrossBioAssay_mean_and_p_values acrossBioAssay_mean_and_standard_deviation acrossBioAssay_mean_and_variance across_bioassay_data_set_function activity_units_per_ml ad_libitum add agar agar_stab age alexa_350 alexa_430 alexa_488 alexa_532 alexa_546 alexa_568 alexa_594 alexa_633 alexa_660 alexa_680 all_pairs amino_acid_primary_sequence_record aminosilane amol aneuploid antibody array_manufacture_software array_manufacturer array_manufacturing array_platform_variation_design array_scanner arrayer atmosphere aunt averaged_intensity barrier_facility bedding beginning_of_stage behavior_design behavioral_design_type behavioral_stimulus bibliographic_record binding_site_identification_design bioassay_data_transformation_software bioassay_replicate_reduction biological_fluid_collection biological_replicate biological_resource_record biomaterial_provider biopsy biosequence_provider biotin birth blood book boolean brother cDNA_clone candela candelas_per_square_meter cc cell cell_component_comparison_design cell_cycle_design cell_line cell_lysate cell_ontology cell_type cell_type_comparison_design cells_per_ml cellular_modification_design cellular_process_design centrifuge cfu_per_ml change_biomaterial_characteristics change_humidity change_light change_temperature chrome_border chromosomal_deletion chromosomal_duplication chromosomal_insertion chromosomal_inversion chromosomal_substitution chromosomal_translocation chromosome circadian_rhythm_design clinical_history_design clinical_information clinical_record clinical_treatment clone_of_unknown_source clustered_data clustering_software cm co-expression_design coitus collapsed_spot_replicate comparative_genome_hybridization_design compound_based_treatment compound_record compound_treatment_design computational_feature computed_amino_acid_sequence_feature_record computed_nucleic_acid_sequence_feature_record computed_protein_structure_record computer concentrate condition_specificity consensus_DNA consensus_mRNA consortium_member consultant control_biosequence control_buffer control_design_element_group_type control_empty control_genomic_DNA control_hybridization_quality control_label control_reporter_size control_spike_calibration control_unknown_type cosine_distance cosmid count cpm ctDNA curated_amino_acid_sequence_record curated_gene_record curated_nucleic_acid_sequence_feature_record curator cytoplasmic_RNA data_analyst data_coder date daughter days decontaminate degrees_C degrees_F deleted_term development_or_differentiation_design developmental_stage diameter_aberration differential_expression differential_expression_software dilute diploid disease_staging disease_state disease_state_design displaced_feature_or_zone dissect dl dose_response_design double_stranded dpm ds_oligo dye_swap_design dye_swap_merge dye_swap_quality_control dye_swap_replicate dye_swap_replicate_reduction eVOC eclosion egg_laying element_design ellipsoid_feature environmental_history_design ex_vivo_design exemplar_mRNA exon experimental_and_computational_feature experimental_design_element_group_type experimental_feature extract fM family_history_design father feature_extraction feature_extraction_software feces feeding female fertilization fg filtered_data fl flag_filter flip-dye_consistency float fmol forward fractionate freeze_dried_sample french_railway_distance fresh_sample frozen_sample frozen_storage function_record funder g g_per_L gene gene_fragment gene_knock_in gene_knock_out genetic_modification genetic_modification_design genetic_variation genomic_DNA genomic_region_amplification genotyping_design germination glass gram_percent granddaughter grandfather grandmother grandson grow growth_condition_design half-life haploid hardware_manufacturer hardware_variation_design harvest hatching heating_block heavy_background hermaphrodite histological_slide_preparation homogenizer hours hybridization hybridization_chamber hybridization_station image_acquisition image_acquisition_software image_record imprinting_design in_medium in_situ_oligo_features in_vitro_design in_vivo_design inconclusive incubate individual individual_genetic_characteristic individual_genetic_characteristics_design induced_mutation infect injury_design innate_behavior_design inoculate institution integer intergenic intramuscular_injection intraperitoneal_injection intravenous intron investigator irradiate irregular_shape is_contaminated is_expressed_design iterative_mean_log_centering jackknife_Pearson_correlation journal_article kat_per_L kg kg_per_m2 labeling laser_ablation_mark light_duration light_intensity linear_amplification linear_regression_normalization linear_scale linlog_normalization linlog_transformation liquid liquid_handler liquid_handler_software list_of_booleans list_of_floats list_of_integers list_of_negative_floats list_of_negative_integers list_of_nonnegative_floats list_of_nonnegative_integers list_of_nonpositive_floats list_of_nonpositive_integers list_of_positive_floats list_of_positive_integers list_of_strings loess_global_normalization loess_group_normalization loess_normalization loess_scaled_group_normalization log_base_10 log_base_2 log_base_e log_ratio long_oligo loop_design low_intensity_filter lowess_global_normalization lowess_group_normalization lowess_normalization lowess_scaled_group_normalization lumen lux m mL_per_L mM mOsm_per_kg_H2O mRNA male manhattan_distance mating_type_a mating_type_alpha mating_type_h_minus mating_type_h_plus mean_and_coefficient_of_variation mean_and_confidence_indicators mean_and_p_values mean_and_standard_deviation mean_and_variance mean_log_centering mean_log_normalization media median_log_centering median_log_normalization merged_term metastatic_site mg mg_per_kg_per_day mg_per_ml microarray_experiment_record microeinstein_per_minute_and_square_meter microeinstein_per_second_and_square_meter micromole_per_second_and_square_meter minutes missing_feature_or_zone mix_by_inversion mix_by_pipette mix_by_vortex mix_general mixed_design_element_group_type mixed_sex ml ml_per_kg mm mol molecular_mixture molecules monosomy months mother moving_average ms mtDNA multiple_testing_correction negative negative_float negative_integer ng nitrocellulose nl nm nmol no non-targeted_transgenic_variation_design nonnegative_float nonnegative_integer nonpositive_float nonpositive_integer normalization_testing_design normalized_intensities normalized_ratios not_extract not_sequence_verified not_uniform nuclear_RNA nucleic_acid_extraction nucleic_acid_primary_sequence_record number_per_day nutrients nylon oligo_synthesizer oligosomy online_resource ontology_record openGALEN operating_system operator_variation_design operon operon_identification_design optimization_design oral_gavage organellar_DNA organellar_RNA organism organism_part organism_part_comparison_design organism_status organism_status_design pH pM paraffin_sample pathogenicity_design pathway_record pearson_correlation_coefficient pedigree_record peer_review_quality_control percent_confluence percent_purity percent_vol_per_vol percent_weight_per_vol percent_weight_per_weight pfu_per_ml pg phylogeny_record physical_characteristics physiological_process_design pl place planting plasmid pmol polyA_RNA polylysine polypeptide polyploid polysomy pool population_density positive positive_float positive_integer postmortem predicted_gene premortem preservation primary_protein_structure_record primary_site promoter protein purify quality_control_testing_design quantile_normalization quantile_normalization_protocol_type rRNA_gene ratio ratio_statistics_normalization real_time_PCR_quality_control rectangular_feature reference_design relative relative_humidity remove replaced_term replicate_analysis replicate_design resuspend reverse reverse_transcription reverse_transcription_PCR_quality_control sacrifice sampling_time_point seconds secreted_protein_identification_design seed_dormancy self_vs_self_design semisolid set_temperature sex sex_design short_oligo signal signal_log_ratio silicon single_stranded sister slice_analysis snRNA_gene software_manufacturer software_variation_design soil son sonicator sowing species_design species_specific_design_element_group_type specified_biomaterial_action spectrophotometer spike_quality_control spin split split_term spotted_antibody_features spotted_colony_features spotted_ds_DNA_features spotted_protein_features spotted_ss_PCR_amplicon_features spotted_ss_oligo_features square_feature ss_oligo starvation stimulated_design_type stimulus_or_stress_design store strain_or_line strain_or_line_design string_datatype subcutaneous submitter synthetic_DNA synthetic_RNA tRNA_gene tau_rank_correlation technical_replicate temperature thermal_cycler tiling_path_design time_series_design timepoint total_RNA total_intensity_normalization total_intensity_normalization_paired total_intensity_normalization_single transcript transcript_identification_design transfect transfection translational_bias_design trisomy tumor_grading uM ug ul um umol uncentered_Pearson_correlation uncle unknown_basis_feature unknown_experiment_design_type unknown_protocol_type unknown_sequence unknown_sex unknown_substrate_type unknown_surface_type unscaled urine us vacuum_dryer vector version_1.1.7 version_1.1.8 version_1.1.9 version_1.2.0 version_1.3.0 version_1.3.1 virus vortexer wait wash wash_station water waterbath weeks whole_organism wild_type within_bioassay_data_set_function x_times years yes

class Action

definition:
Procedures used during treatment.

superclasses:
    BioMaterialPackage
    BiologicalFactorCategory
known subclasses:
    AtomicAction
    ComplexAction
properties:
    unique_identifier MO_193
    class_role abstract
    class_source ontology

class Age

definition:
The time period elapsed since an identifiable point in the life cycle of an organism. If a developmental stage is specified, the identifiable point would be the beginning of that stage. Otherwise the identifiable point must be specified such as planting (e.g. 3 days post planting).

superclasses:
    BioMaterialCharacteristics
properties:
    unique_identifier MO_178
    class_role abstract
    class_source ontology
constraints:
    restriction: has_measurement has-class Measurement
    restriction: has_maximum_measurement has-class Measurement
    restriction: has_initial_time_point has-class InitialTimePoint

class Allele

definition:
One of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on phenotype or sequence. Polymorphisms are included in this definition.

superclasses:
    IndividualGeneticCharacteristics
properties:
    unique_identifier MO_58
    class_role concrete
    class_source ontology
used in individuals:
    wild_type

class ArrayDesignPackage

definition:
MAGE package that describes the array layout and design. The array may be physical or virtual.

superclasses:
    MGEDCoreOntology
known subclasses:
    DesignElementGroup
    DesignElementGroupType
    FeatureShape
    PhysicalArrayDesign
    SurfaceType
    TechnologyType
properties:
    unique_identifier MO_33
    class_role abstract
    class_source mage

class ArrayGroup

definition:
An array group is a physical platform that contains one or more arrays that are separately addressable or a virtual grouping of arrays.

superclasses:
    ArrayPackage
properties:
    unique_identifier MO_34
    class_role concrete
    class_source mage
constraints:
    restriction: has_fiducials has-class Fiducial
    restriction: has_type has-class SubstrateType

class ArrayPackage

definition:
MAGE package for describing the process by which arrays were manufactured.

superclasses:
    MGEDCoreOntology
known subclasses:
    ArrayGroup
    DefectType
    FeatureDefect
    Fiducial
    FiducialType
    SubstrateType
    ZoneDefect
properties:
    unique_identifier MO_107
    class_role abstract
    class_source mage

class Atmosphere

definition:
The atmospheric conditions used to culture or grow an organism.

superclasses:
    GrowthCondition
properties:
    unique_identifier MO_219
    class_role abstract
    class_source ontology
constraints:
    restriction: has_atmospheric_component has-class Compound

class AtomicAction

definition:
An atomic action is a single step process on the biomaterial, e.g. mix by inversion, wait, add

superclasses:
    Action
properties:
    unique_identifier MO_68
    class_role concrete
    class_source ontology
used in individuals:
    add
    change_humidity
    change_light
    change_temperature
    concentrate
    dilute
    mix_by_inversion
    mix_by_pipette
    mix_by_vortex
    mix_general
    place
    remove
    resuspend
    set_temperature
    specified_biomaterial_action
    spin
    wait

class AuditAndSecurityPackage

definition:
MAGE package for contacts including organizations and people.

superclasses:
    MGEDCoreOntology
known subclasses:
    Contact
    Roles
properties:
    unique_identifier MO_172
    class_role abstract
    class_source mage

class BarrierFacility

definition:
Rating of containment system for the protection of organisms from infectious agents.

superclasses:
    GrowthCondition
properties:
    unique_identifier MO_97
    class_role abstract
    class_source ontology

class Bedding

definition:
Refers to the bedding material present in an animals housing.

superclasses:
    EnvironmentalHistory
properties:
    unique_identifier MO_154
    class_role place_holder
    class_source ontology

class BibliographicReference

definition:
A bibliographic reference is a published citation in a journal, book, other format e.g. web resource

superclasses:
    DescriptionPackage
properties:
    unique_identifier MO_201
    class_role concrete
    class_source mage
constraints:
    restriction: has_pages has-class string
    restriction: has_issue has-class string
    restriction: has_editor has-class string
    restriction: has_URI has-class URI
    restriction: has_volume has-class string
    restriction: has_authors has-class string
    restriction: has_type has-class PublicationType
    restriction: has_year has-class date
    restriction: has_publication has-class string
    restriction: has_publisher has-class string
    restriction: has_title has-class string

class BioAssay

definition:
A bioassay is an abstract class representing physical and computational groupings of biomaterials and arrays.

superclasses:
    BioAssayPackage
known subclasses:
    DerivedBioAssay
    PhysicalBioAssay
properties:
    unique_identifier MO_56
    class_role abstract
    class_source mage

class BioAssayData

definition:
BioAssayData refers to the data files including images generated from one or more BioAssays.

superclasses:
    BioAssayDataPackage
properties:
    unique_identifier MO_40

class BioAssayDataCluster

definition:
A grouping of bioassay data that has been organized by one or more mathematical functions into nodes.

superclasses:
    HigherLevelAnalysisPackage
properties:
    unique_identifier MO_116
    class_role concrete
    class_source mage
constraints:
    restriction: has_nodes has-class Node

class BioAssayDataPackage

definition:
MAGE package for BioAssayData.

superclasses:
    MGEDExtendedOntology
known subclasses:
    BioAssayData
    Transformation
properties:
    unique_identifier MO_186

class BioAssayPackage

definition:
MAGE package for bioassay.

superclasses:
    MGEDCoreOntology
known subclasses:
    BioAssay
    DerivedBioAssayType
    ImageFormat
properties:
    unique_identifier MO_0
    class_role abstract
    class_source mage

class BioMaterial

definition:
Description of the processing state of the biomaterial for use in the microarray hybridization.

superclasses:
    BioMaterialPackage
known subclasses:
    BioSample
    BioSource
    LabeledExtract
properties:
    unique_identifier MO_226
    class_role abstract
    class_source mage
constraints:
    restriction: has_type has-class MaterialType
    restriction: has_biomaterial_characteristics has-class BioMaterialCharacteristics

class BioMaterialCharacteristicCategory

definition:
General descriptor of a BioMaterialCharacteristic category. Such as strain or line where the name of the strain or line is encoded in the FactorValue.

superclasses:
    BiologicalFactorCategory
properties:
    unique_identifier MO_100
used in individuals:
    age
    biomaterial_provider
    cell_line
    cell_type
    clinical_information
    clinical_treatment
    developmental_stage
    disease_staging
    disease_state
    individual
    individual_genetic_characteristic
    organism
    organism_part
    organism_status
    physical_characteristics
    sampling_time_point
    sex
    strain_or_line
    tumor_grading

class BioMaterialCharacteristics

definition:
Properties of the biomaterial before treated in any manner for the purposes of the experiment.

superclasses:
    BioMaterialPackage
    BiologicalFactorCategory
known subclasses:
    Age
    BioMaterialPurity
    Biometrics
    BioSourceProvider
    BioSourceType
    CellLine
    CellType
    CellularComponent
    ChromosomalAberrationClassification
    ClinicalTreatment
    DevelopmentalStage
    DiseaseStaging
    DiseaseState
    EnvironmentalHistory
    GeneticModification
    Histology
    Individual
    IndividualGeneticCharacteristics
    Observation
    Organism
    OrganismPart
    OrganismStatus
    Phenotype
    Serotype
    Sex
    StrainOrLine
    TargetedCellType
    Test
    TestResult
    TestType
    TumorGrading
properties:
    unique_identifier MO_5
    class_role abstract
    class_source ontology

class BioMaterialPackage

definition:
Description of the source of the nucleic acid used to generate labeled material for the microarray experiment.

superclasses:
    MGEDCoreOntology
known subclasses:
    Action
    BioMaterial
    BioMaterialCharacteristics
    BioSampleType
    FamilyMember
    FamilyRelationship
    InitialTimePoint
    MaterialType
    Treatment
properties:
    unique_identifier MO_182
    class_role abstract
    class_source mage

class BioMaterialPurity

definition:
A measure of homogeneity of a biomaterial. For example, an expression of the percentage of a tumor biopsy that is tumor cells.

superclasses:
    BioMaterialCharacteristics
properties:
    unique_identifier MO_20
    class_role abstract
    class_source ontology

class BioMolecularAnnotation

definition:
BioMolecularAnnotation experiment design types are those which are designed to investigate functions, processes, locations and identity at the molecular level e.g. binding site identification, genotyping.

superclasses:
    ExperimentDesignType
properties:
    unique_identifier MO_213
    class_role concrete
    class_source ontology
used in individuals:
    RNA_stability_design
    binding_site_identification_design
    co-expression_design
    comparative_genome_hybridization_design
    genotyping_design
    operon_identification_design
    secreted_protein_identification_design
    tiling_path_design
    transcript_identification_design
    translational_bias_design
    unknown_experiment_design_type

class BioSample

definition:
The BioSource after any treatment.

superclasses:
    BioMaterial
properties:
    unique_identifier MO_93
    class_role concrete
    class_source mage
constraints:
    restriction: has_type has-class BioSampleType
    restriction: has_been_treated has-class Treatment

class BioSampleType

definition:
Used to tell when the BioSample is an extract or not.

superclasses:
    BioMaterialPackage
properties:
    unique_identifier MO_161
    class_role concrete
    class_source ontology
used in individuals:
    extract
    not_extract

class BioSequence

definition:
A representation of a DNA, RNA, or protein sequence.

superclasses:
    BioSequencePackage
properties:
    unique_identifier MO_163
    class_role concrete
    class_source mage
constraints:
    restriction: has_species has-class Organism
    restriction: has_type has-class PolymerType
    restriction: has_type has-class BioSequenceType

class BioSequencePackage

definition:
MAGE package for biological sequences (biosequence).

superclasses:
    MGEDCoreOntology
known subclasses:
    BioSequence
    BioSequenceType
    PolymerType
    SeqFeatureBasis
properties:
    unique_identifier MO_191
    class_role abstract
    class_source mage

class BioSequenceType

definition:
Controlled terms for descriptors indicating the type of biosequence. Types may be physical (e.g. BAC, cDNA clone), or computational (e.g. unigene cluster, consensus).

superclasses:
    BioSequencePackage
known subclasses:
    PhysicalBioSequenceType
    TheoreticalBioSequenceType
properties:
    unique_identifier MO_152
    class_role abstract
    class_source ontology

class BioSource

definition:
The BioSource is the original source material before any treatment events.

superclasses:
    BioMaterial
properties:
    unique_identifier MO_77
    class_role concrete
    class_source mage

class BioSourceProvider

definition:
The resource (e.g. company, hospital, geographical location) used to obtain or purchase the biomaterial.

superclasses:
    BioMaterialCharacteristics
properties:
    unique_identifier MO_230
    class_role abstract
    class_source ontology
constraints:
    restriction: has_owner has-class Person
    restriction: has_donor has-class Organization

class BioSourceType

definition:
The form in which the BioMaterial was obtained/maintained e.g. frozen, fresh etc. Note can be used to describe BioSamples as well as BioSources.

superclasses:
    BioMaterialCharacteristics
properties:
    unique_identifier MO_95
    class_role concrete
    class_source ontology
used in individuals:
    agar_stab
    freeze_dried_sample
    fresh_sample
    frozen_sample
    paraffin_sample
    urine

class BiologicalFactorCategory

definition:
Factors that relate to properties of the biomaterial, its treatment, or its growth.

superclasses:
    ExperimentalFactorCategory
known subclasses:
    Action
    BioMaterialCharacteristicCategory
    BioMaterialCharacteristics
    Compound
properties:
    unique_identifier MO_190
    class_role abstract
    class_source ontology

class BiologicalProperty

definition:
A biological property experiment design type is where an intrinsic characteristic of an organism(s) or biological system is examined.

superclasses:
    ExperimentDesignType
properties:
    unique_identifier MO_224
    class_role concrete
    class_source ontology
used in individuals:
    cell_component_comparison_design
    cell_cycle_design
    cell_type_comparison_design
    cellular_process_design
    development_or_differentiation_design
    imprinting_design
    individual_genetic_characteristics_design
    innate_behavior_design
    is_expressed_design
    organism_part_comparison_design
    organism_status_design
    physiological_process_design
    sex_design
    species_design
    strain_or_line_design
    unknown_experiment_design_type

class Biometrics

definition:
Physical properties of the BioMaterial e. g. mass or height

superclasses:
    BioMaterialCharacteristics
properties:
    unique_identifier MO_129
    class_role abstract
    class_source ontology
constraints:
    restriction: has_cubic_volume has-class Measurement
    restriction: has_mass has-class Measurement
    restriction: has_diameter has-class Measurement
    restriction: has_length has-class Measurement
    restriction: has_height has-class Measurement
    restriction: has_individual has-class Individual
    restriction: has_organism_part has-class OrganismPart

class CancerSite

definition:
class to hold instances used as the filler for the property has_cancer_site

superclasses:
    MGEDCoreOntology
properties:
    unique_identifier MO_26
    class_role concrete
    class_source ontology
used in individuals:
    metastatic_site
    primary_site

class CellLine

definition:
The identifier for the established culture of a metazoan cell if one was used as a biomaterial.

superclasses:
    OntologyEntry
    BioMaterialCharacteristics
properties:
    unique_identifier MO_49
    class_role abstract
    class_source ontology
constraints:
    restriction: has_database has-class CellLineDatabase

class CellLineDatabase

definition:
Database of cell line information.

superclasses:
    Database
properties:
    unique_identifier MO_145
    class_role concrete
    class_source ontology
used in individuals:
    ATCC_Cultures
    CABRI_HLA_typed_B_Cell_lines
    CABRI_Human_and_Animal_Cell_lines
    CABRI_Hybridomas
    CLDB_Human_and_Animal_Cell_Line

class CellType

definition:
CellType, the type of cell used in the experiment if non mixed, if mixed the TargetedCellType should be used, example of instances, epithelial, glial etc.

superclasses:
    BioMaterialCharacteristics
    OntologyEntry
properties:
    unique_identifier MO_135
    class_role abstract
    class_source ontology
constraints:
    restriction: has_database has-class CellTypeDatabase

class CellTypeDatabase

definition:
Database of cell type information.

superclasses:
    Database
properties:
    unique_identifier MO_141
    class_role concrete
    class_source ontology
used in individuals:
    CBIL_CV
    NCI_cell_type_database
    TAIR
    cell_ontology
    eVOC

class CellularComponent

definition:
A structure within a cell, such as an anatomical structure (e.g. rough endoplasmic reticulum or nucleus) or a gene product group (e.g. ribosome, proteasome or a protein dimer).

superclasses:
    OntologyEntry
    BioMaterialCharacteristics
properties:
    unique_identifier MO_1020
    class_role abstract
    class_source ontology
constraints:
    restriction: has_database has-class CellularComponentDatabase

class CellularComponentDatabase

definition:
A resource for terms to describe cellular components, e.g. GO Cellular Component ontology.

superclasses:
    Database
properties:
    unique_identifier MO_1021
    class_role concrete
    class_source ontology
used in individuals:
    GeneOntology

class ChromosomalAberration

definition:
An abnormality of a chromosome's number or structure, which excludes simple changes in sequence and is usually detectable by cytogenetic and microscopic techniques such as FISH.

superclasses:
    DeprecatedTerms
properties:
    deprecation_old_restriction some|has_chromosomal_aberration_classification|ChromosomalAberrationClassification
    deprecation_in_version 1.1.7
    unique_identifier MO_78
    class_role abstract
    class_source ontology
    deprecation_reason deleted_term
    deprecation_replacement_term ChromosomalAberration
constraints:
    restriction: has_reason_for_deprecation has-class deleted_term
    restriction: has_chromosomal_aberration_classification has-class ChromosomalAberrationClassification
    restriction: deprecated_from_version has-class version_1.1.7

class ChromosomalAberrationClassification

definition:
An irregularity in the number or structure of chromosomes, usually in the form of a gain (duplication), loss (deletion), exchange (translocation), or alteration in sequence (inversion) of genetic material. Excludes simple changes in sequence such as mutations, and is usually detectable by cytogenetic and microscopic techniques such as FISH.

superclasses:
    BioMaterialCharacteristics
properties:
    unique_identifier MO_6
    class_role concrete
    class_source ontology
used in individuals:
    chromosomal_deletion
    chromosomal_duplication
    chromosomal_insertion
    chromosomal_inversion
    chromosomal_translocation
    genomic_region_amplification
    oligosomy
    polysomy

class ClinicalHistory

definition:
The BioMaterial's (i.e., the patient's) medical record as background information relevant to the experiment.

superclasses:
    EnvironmentalHistory
properties:
    unique_identifier MO_189
    class_role abstract
    class_source ontology
constraints:
    restriction: has_clinical_treatment has-class ClinicalTreatment
    restriction: has_clinical_record has-class OntologyEntry
    restriction: has_clinical_finding has-class TestResult
    restriction: has_prior_disease_state has-class DiseaseState
    restriction: has_test_type has-class TestType

class ClinicalTreatment

definition:
The current clinical treatment(s) of the patient from which the biosource is derived.

superclasses:
    BioMaterialCharacteristics
    OntologyEntry
properties:
    unique_identifier MO_69
    class_role abstract
    class_source ontology
constraints:
    restriction: has_database has-class ClinicalTreatmentDatabase

class ClinicalTreatmentDatabase

definition:
Database of clinical treatment information

superclasses:
    Database
properties:
    unique_identifier MO_114
    class_role concrete
    class_source ontology

class ComplexAction

definition:
Complex actions are composed of multiple steps (as opposed to AtomicAction) e.g. mRNA labeling, protein purification.

superclasses:
    Action
properties:
    unique_identifier MO_90
    class_role concrete
    class_source ontology
used in individuals:
    PCR_amplification
    acclimatization
    behavioral_stimulus
    biological_fluid_collection
    biopsy
    change_biomaterial_characteristics
    compound_based_treatment
    decontaminate
    dissect
    fractionate
    genetic_modification
    grow
    harvest
    histological_slide_preparation
    hybridization
    incubate
    inoculate
    irradiate
    labeling
    linear_amplification
    nucleic_acid_extraction
    pool
    preservation
    purify
    reverse_transcription
    sacrifice
    specified_biomaterial_action
    split
    starvation
    store
    timepoint
    transfect
    wash

class Compound

definition:
A drug, solvent, chemical, etc., with a property that can be measured such as concentration.

superclasses:
    OntologyEntry
    BiologicalFactorCategory
known subclasses:
    LabelCompound
properties:
    unique_identifier MO_70
    class_role abstract
    class_source ontology
constraints:
    restriction: has_measurement has-class Compound
    restriction: is_solvent has-class boolean
    restriction: has_database has-class CompoundDatabase

class CompoundDatabase

definition:
Database of compound information.

superclasses:
    Database
properties:
    unique_identifier MO_151
    class_role concrete
    class_source ontology
used in individuals:
    ChEBI
    ChemID
    NCI_compound_database

class ConcentrationUnit

definition:
Units used for concentration measurements.

superclasses:
    Unit
known subclasses:
    ConcentrationUnitOther
properties:
    unique_identifier MO_61
    class_role concrete
    class_source ontology
used in individuals:
    M
    U_per_L
    fM
    g_per_L
    gram_percent
    mL_per_L
    mM
    mg_per_ml
    pM
    percent_vol_per_vol
    percent_weight_per_vol
    percent_weight_per_weight
    uM

class ConcentrationUnitOther

definition:
Concentration units not specified in MAGE.

superclasses:
    ConcentrationUnit
properties:
    unique_identifier MO_86
    class_role concrete
    class_source ontology
used in individuals:
    cells_per_ml
    cfu_per_ml
    kat_per_L
    mOsm_per_kg_H2O
    mg_per_kg_per_day
    ml_per_kg
    pH
    percent_confluence
    percent_purity
    pfu_per_ml
    x_times

class Contact

definition:
Organizations or individuals that may be contacted.

superclasses:
    AuditAndSecurityPackage
known subclasses:
    Organization
    Person
properties:
    unique_identifier MO_147
    class_role abstract
    class_source mage
constraints:
    restriction: has_address has-class string
    restriction: has_phone has-class string
    restriction: has_URI has-class URI
    restriction: has_email has-class string
    restriction: has_fax has-class string
    restriction: has_toll_free_phone has-class string
    restriction: has_type has-class Roles

class ControlType

definition:
Controlled terms for descriptors for the type of control design element.

superclasses:
    DesignElementPackage
properties:
    unique_identifier MO_50
    class_role concrete
    class_source ontology
used in individuals:
    control_biosequence
    control_buffer
    control_empty
    control_genomic_DNA
    control_hybridization_quality
    control_label
    control_reporter_size
    control_spike_calibration
    control_unknown_type

class Cultivar

definition:
a plant variety obtained in agriculture in horticulture

superclasses:
    StrainOrLine
properties:
    unique_identifier MO_124
    class_role abstract
    class_source ontology
constraints:
    restriction: has_database has-class StrainOrLineDatabase

class DataTransformationProtocolType

definition:
The process by which derived BioAssays are created from measured BioAssays and/or derived BioAssays.

superclasses:
    ProtocolType
properties:
    unique_identifier MO_165
    class_role concrete
    class_source ontology
used in individuals:
    across_bioassay_data_set_function
    dye_swap_merge
    flag_filter
    linlog_transformation
    loess_global_normalization
    loess_group_normalization
    loess_scaled_group_normalization
    lowess_global_normalization
    lowess_group_normalization
    lowess_scaled_group_normalization
    mean_log_normalization
    median_log_normalization
    moving_average
    quantile_normalization_protocol_type
    replicate_analysis
    total_intensity_normalization_paired
    total_intensity_normalization_single
    within_bioassay_data_set_function

class DataType

definition:
Primitive data types found in computing languages such as float, boolean, etc.

superclasses:
    MGEDCoreOntology
properties:
    unique_identifier MO_125
    class_role concrete
    class_source ontology
used in individuals:
    boolean
    date
    float
    integer
    list_of_booleans
    list_of_floats
    list_of_integers
    list_of_negative_floats
    list_of_negative_integers
    list_of_nonnegative_floats
    list_of_nonnegative_integers
    list_of_nonpositive_floats
    list_of_nonpositive_integers
    list_of_positive_floats
    list_of_positive_integers
    list_of_strings
    negative_float
    negative_integer
    nonnegative_float
    nonnegative_integer
    nonpositive_float
    nonpositive_integer
    positive_float
    positive_integer
    string_datatype

class Database

definition:
Identifiable resource containing data or external ontologies or controlled vocabularies which has uniquely identifiable records.

superclasses:
    DescriptionPackage
known subclasses:
    CellLineDatabase
    CellTypeDatabase
    CellularComponentDatabase
    ClinicalTreatmentDatabase
    CompoundDatabase
    DevelopmentalStageDatabase
    DiseaseStagingDatabase
    DiseaseStateDatabase
    GeographicLocationDatabase
    HistologyDatabase
    ObservationDatabase
    OrganismDatabase
    OrganismPartDatabase
    PhenotypeDatabase
    SequenceOntologyDatabase
    StrainOrLineDatabase
    TargetedCellTypeDatabase
    TestTypeDatabase
    TumorGradingDatabase
properties:
    unique_identifier MO_118
    class_role abstract
    class_source ontology
constraints:
    restriction: has_version has-class string
    restriction: has_URI has-class URI

class DatabaseEntryType

definition:
Controlled set of descriptors for the type of database record such as a protein record (in SWISS-PROT) or a gene object (in SGD).

superclasses:
    DescriptionPackage
properties:
    unique_identifier MO_157
    class_role concrete
    class_source ontology
used in individuals:
    amino_acid_primary_sequence_record
    bibliographic_record
    biological_resource_record
    clinical_record
    compound_record
    computed_amino_acid_sequence_feature_record
    computed_nucleic_acid_sequence_feature_record
    computed_protein_structure_record
    curated_amino_acid_sequence_record
    curated_gene_record
    curated_nucleic_acid_sequence_feature_record
    function_record
    image_record
    microarray_experiment_record
    nucleic_acid_primary_sequence_record
    ontology_record
    pathway_record
    pedigree_record
    phylogeny_record
    primary_protein_structure_record

class DefectType

definition:
Defects associated with features or zones such as those that are missing or moved.

superclasses:
    ArrayPackage
properties:
    unique_identifier MO_16
    class_role concrete
    class_source ontology
used in individuals:
    diameter_aberration
    displaced_feature_or_zone
    heavy_background
    irregular_shape
    missing_feature_or_zone
    not_uniform

class DeliveryMethod

definition:
Method used to deliver a compound for treatment.

superclasses:
    MGEDExtendedOntology
properties:
    unique_identifier MO_223
used in individuals:
    ad_libitum
    feeding
    in_medium
    intramuscular_injection
    intraperitoneal_injection
    intravenous
    oral_gavage
    subcutaneous

class DeprecatedTerms

definition:
Class to hold deprecated instances and classes.

superclasses:
    MGEDCoreOntology
known subclasses:
    ChromosomalAberration
    FactorValueDependency
    FactorValueSet
    IndividualChromosomalAbnormality
properties:
    unique_identifier MO_206
    class_role concrete
    class_source ontology
constraints:
    restriction: has_reason_for_deprecation has-class DeprecationReason
used in individuals:
    BAC
    EST
    Hfr
    NCI_Thesaurus
    ORF
    PAC
    PCR_amplicon
    PCR_primer<